Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249891 | 0.79 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8899182 | 0.79 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1413253 | 0.79 | MGAM (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11274143 | 0.79 | ZDHHC7 (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL13099488 | 0.78 | ALDH1A1 (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11495744 | 0.77 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL133872 | 0.76 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1444812 | 0.76 | TET2 (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12451759 | 0.76 | MGAM (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL27848612 | 0.76 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629419-A | Process for preparing 4-mercaptopyrrolidine intermediate compounds and a process for their use in preparing carbapenem -2-em-3 carboxylic acids | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0713866-A1 | Process for preparing 4-mercaptopyrrolidine compound | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-29 | — | — | EP | disclosed |