Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413253 | 0.77 | MGAM (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8899182 | 0.77 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3249891 | 0.77 | TSHR (0.44) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL11274143 | 0.77 | ZDHHC7 (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL27562342 | 0.76 | TRPA1 (0.33) | ALDH1A1TRPA1 | |
| SCHEMBL11495744 | 0.76 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8896554 | 0.76 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1444812 | 0.74 | TET2 (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12451759 | 0.74 | MGAM (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL27848612 | 0.74 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116539780-A | Method for simultaneously detecting aminolevulinic acid hydrochloride intermediate and 5 impurities | 湖南先施制药有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-9689840-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugate | BIO-RAD LABORATORIES, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-9689840-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugate | BIO-RAD LABORATORIES, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-9689840-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugate | BIO-RAD LABORATORIES, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160223491-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATE | BIO RAD LABORATORIES INC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160223491-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATE | BIO RAD LABORATORIES INC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160223491-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATE | BIO RAD LABORATORIES INC (US) | 2016-08-04 | — | — | US | disclosed |
| US-9274103-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugates | BIO-RAD LABORATORIES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9274103-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugates | BIO-RAD LABORATORIES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9274103-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugates | BIO-RAD LABORATORIES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-8536162-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugates | BIO-RAD LABORATORIES, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8536162-B2 | Conjugates of 1,4,7-triazacyclononanes, dinuclear metal complexes of such conjugates, and methods of use for both 1,4,7-triazacyclononanes and conjugates | BIO-RAD LABORATORIES, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| EP-2547666-A1 | CONJUGATES OF 1,4,7-TRIAZA-CYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZA-CYCLONONANES AND CONJUGATES | Bio-Rad Laboratories, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20120058565-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATES | BIO-RAD LABORATORIES, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058565-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATES | BIO-RAD LABORATORIES, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058565-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATES | BIO-RAD LABORATORIES, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2011115802-A1 | CONJUGATES OF 1,4,7-TRIAZA-CYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZA-CYCLONONANES AND CONJUGATES | BIO-RAD LABORATORIES, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011115802-A1 | CONJUGATES OF 1,4,7-TRIAZA-CYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZA-CYCLONONANES AND CONJUGATES | BIO-RAD LABORATORIES, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-7339073-B2 | Method for obtaining 5-halogenolaevulinic acid alkyl esters | ALDENKORTT SVEN | 2008-03-04 | — | — | US | disclosed |
| US-20050070727-A1 | Method for obtaining 5-halogenolaevulinic acid alkyl esters | ALDENKORTT DR SVEN (DE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160223491-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATE | CYP24A1, PTMS, CYP27B1 | TSHR 3547/4885HSD17B10 85/4885MGAM 3289/4885 |
| US-20120058565-A1 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATES | CYP24A1, PTMS, CYP27B1 | TSHR 3556/4885HSD17B10 83/4885MGAM 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.