Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944564 | 0.89 | HSD17B10 (0.39) | TSHRTDP1L3MBTL1HSD17B10MAPT | |
| SCHEMBL2907995 | 0.84 | ALDH1A1 (0.44) | L3MBTL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL4755372 | 0.72 | TSHR (0.39) | TSHRTDP1L3MBTL1HSD17B10MAPT | |
| SCHEMBL4880017 | 0.71 | TSHR (0.38) | TSHRTDP1L3MBTL1HSD17B10MAPT | |
| SCHEMBL4608922 | 0.70 | CYP2C19 (0.38) | TSHRTDP1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL7382729 | 0.70 | TSHR (0.37) | TSHRTDP1L3MBTL1HSD17B10MAPT | |
| SCHEMBL19040319 | 0.70 | ALDH1A1 (0.48) | TDP1HSD17B10MAPTALDH1A1MEN1 | |
| SCHEMBL9396727 | 0.65 | KMT2A (0.40) | TSHRTDP1HSD17B10ALDH1A1MEN1 | |
| Acetic Acid SCHEMBL27721273 | 0.65 | HSD17B10 (0.58) | TSHRTDP1L3MBTL1HSD17B10MAPT | |
| SCHEMBL30937544 | 0.64 | AKR1C1 (0.46) | TSHRTDP1L3MBTL1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618842-A | TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES | LIFEGROUP S.P.A. (IT) | 1997-04-08 | — | — | US | claimed |
| US-5618842-A | TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES | LIFEGROUP S.P.A. (IT) | 1997-04-08 | — | — | US | disclosed |