Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.55 |
| ▸ | NPY2R | P49146 | 3/20 | 0.55 |
| ▸ | NPY4R | P50391 | 3/20 | 0.55 |
| ▸ | GHSR | Q92847 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895453 | 1.00 | NPY1R (0.55) | NPY1RNPY2RNPY4RGHSR | |
| SCHEMBL8896669 | 0.98 | GHSR (0.55) | NPY1RNPY2RNPY4RGHSR | |
| SCHEMBL8896981 | 0.94 | GHSR (0.61) | NPY1RNPY2RNPY4RGHSR | |
| SCHEMBL8894741 | 0.94 | GHSR (0.61) | NPY1RNPY2RNPY4RGHSR | |
| SCHEMBL8895364 | 0.94 | GHSR (0.61) | NPY1RNPY2RNPY4RGHSR | |
| SCHEMBL8894890 | 0.93 | GHSR (0.59) | GHSR | |
| SCHEMBL12464358 | 0.93 | NPY1R (0.59) | NPY1RNPY2RNPY4R | |
| SCHEMBL8894262 | 0.92 | ECE1 (0.60) | GHSR | |
| SCHEMBL8896053 | 0.92 | ECE1 (0.60) | GHSR | |
| SCHEMBL8894510 | 0.92 | IL1RN (0.54) | NPY1RNPY2RNPY4RGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | claimed |
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |