Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.59 |
| ▸ | NPY2R | P49146 | 3/20 | 0.59 |
| ▸ | NPY4R | P50391 | 3/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464476 | 0.93 | MC5R (0.61) | NPY1RNPY2RNPY4R | |
| SCHEMBL8896673 | 0.93 | NPY1R (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL8895453 | 0.93 | NPY1R (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL8896669 | 0.91 | GHSR (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL8894510 | 0.90 | IL1RN (0.54) | NPY1RNPY2RNPY4RECE1 | |
| SCHEMBL8895429 | 0.90 | IL1RN (0.54) | NPY1RNPY2RNPY4RECE1 | |
| SCHEMBL31722484 | 0.89 | KDM4E (0.62) | ECE1 | |
| SCHEMBL5558360 | 0.89 | ECE1 (0.69) | NPY1RNPY2RNPY4RECE1 | |
| SCHEMBL30291268 | 0.89 | ECE1 (0.69) | NPY1RNPY2RNPY4RECE1 | |
| Hydrochloric Acid SCHEMBL8982603 | 0.88 | KDM4E (0.60) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |