Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452170 | 0.74 | TSHR (0.53) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL8896841 | 0.73 | ALDH1A1 (0.40) | TSHRALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL27506420 | 0.69 | L3MBTL1 (0.55) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL1346095 | 0.69 | TSHR (0.56) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL22283397 | 0.68 | TSHR (0.51) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27593212 | 0.67 | ALDH1A1 (0.57) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5761203 | 0.66 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1KLK7 | |
| Methyl Alcohol SCHEMBL9357302 | 0.66 | CES1 (0.53) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL769363 | 0.66 | TSHR (0.62) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL26460969 | 0.66 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |