Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402447 | 0.89 | DNM1 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRPRKCA | |
| SCHEMBL5805725 | 0.79 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TSHRPRKCAPRKCD | |
| SCHEMBL5088890 | 0.78 | DNM1 (0.31) | DNM1 | |
| SCHEMBL17526883 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL17526575 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL11669709 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL7983818 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL6538583 | 0.76 | DNM1 (0.32) | DNM1 | |
| SCHEMBL30977012 | 0.73 | TSHR (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL8161093 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |