Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526575 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL11669709 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL17526803 | 0.93 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL17526910 | 0.93 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL17526873 | 0.91 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL17527025 | 0.91 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL1657472 | 0.91 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL6523251 | 0.90 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL1556424 | 0.88 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL807201 | 0.87 | DNM1 (0.41) | ALDH1A1SMN1; SMN2LMNATSHRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ALDH1A1 2376/4885SMN1; SMN2 649/4885LMNA 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.