Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.67 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701514 | 0.94 | RAPGEF4 (0.61) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL8897281 | 0.90 | RAPGEF4 (0.67) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL28542938 | 0.88 | RAPGEF4 (0.56) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL17503340 | 0.87 | RAPGEF4 (0.59) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL6029581 | 0.87 | RAPGEF4 (0.54) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL8067239 | 0.87 | RAPGEF4 (0.54) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL8075313 | 0.87 | RAPGEF4 (0.54) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL5543379 | 0.87 | RAPGEF4 (0.54) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL29939003 | 0.87 | RAPGEF4 (0.54) | RAPGEF4KIF11MAPTSIGMAR1TP53 | |
| SCHEMBL7506239 | 0.85 | MTNR1B (0.56) | RAPGEF4MAPTSMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616032-A | Rare earth complex | 东曹株式会社 | 2024-02-27 | — | — | CN | disclosed |
| EP-3071424-B1 | POLYURETHANE SUPPORT FOR NON-PNEUMATIC TIRE | MICHELIN & CIE (FR) | 2021-05-26 | — | — | EP | disclosed |
| US-20160288569-A1 | POLYURETHANE SUPPORT FOR NON-PNEUMATIC TIRE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-10-06 | — | — | US | disclosed |
| EP-3071424-A1 | POLYURETHANE SUPPORT FOR NON-PNEUMATIC TIRE | Compagnie Générale des Etablissements Michelin (FR) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077438-A1 | POLYURETHANE SUPPORT FOR NON-PNEUMATIC TIRE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2015-05-28 | — | — | WO | disclosed |
| CN-1056186-C | Monoclonal antibody against human manganese-superoxide dismutase, method for producing them and use | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| US-5648538-A | Process for preparing diarylamines from arylamines | FUSHUN RESEARCH INSTITUTE OF PETROLEUM AND PETROCHEMICALS (CN) | 1997-07-15 | — | — | US | disclosed |