Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896899 | 0.87 | RAPGEF4 (0.67) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL4701514 | 0.85 | RAPGEF4 (0.61) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL27708481 | 0.84 | MAPT (0.55) | MAPTHTTL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8075313 | 0.82 | RAPGEF4 (0.54) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL6029581 | 0.82 | RAPGEF4 (0.54) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL29939003 | 0.82 | RAPGEF4 (0.54) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5081519 | 0.82 | MAPT (0.63) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL2777971 | 0.81 | CYP3A4 (0.54) | MAPTHTTL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL20049388 | 0.80 | MAPT (0.73) | RAPGEF4MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL26088637 | 0.79 | MAPT (0.50) | MAPTHTTL3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212053-A1 | PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS | PROGENICS PHARMACEUTICALS, INC. | 2011-09-01 | — | — | US | disclosed |
| EP-1030572-A1 | PRODUCT APPLICATOR | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999026508-A1 | PRODUCT APPLICATOR | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212053-A1 | PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS | PIK3CA, AKT1, PIK3R5 | RAPGEF4 675/4885MAPT 3045/4885HTT 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.