Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026302 | 0.75 | FDPS (0.51) | FDPSHSPA5HSPA2CYP3A4ACACB | |
| SCHEMBL8894520 | 0.73 | GABRA5 (0.42) | RENALDH1A1 | |
| SCHEMBL15592495 | 0.71 | FDPS (0.50) | FDPSHSPA5ACACBLMNAXBP1 | |
| SCHEMBL21299172 | 0.70 | FDPS (0.53) | FDPSHSPA5CYP3A4ACACBALDH1A1 | |
| SCHEMBL6385699 | 0.70 | FDPS (0.53) | FDPSHSPA5CYP3A4ACACBALDH1A1 | |
| SCHEMBL24387763 | 0.70 | FDPS (0.45) | FDPSHSPA5HSPA2FFAR2CYP3A4 | |
| SCHEMBL27120255 | 0.70 | FDPS (0.45) | FDPSHSPA5HSPA2FFAR2CYP3A4 | |
| SCHEMBL2047231 | 0.70 | FDPS (0.51) | FDPSACACBLMNAXBP1ALDH1A1 | |
| SCHEMBL2035542 | 0.69 | — | — | |
| SCHEMBL104654 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693619-A | ENZYME INHIBITORS; ADMINISTERED TO TREAT CONGESTIVE HEART FAILURE AND HYPERTENSION | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1997-12-02 | — | — | US | claimed |