Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896265 | 0.90 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2F10 | |
| SCHEMBL8401186 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2PRSS1 | |
| SCHEMBL7397917 | 0.72 | ITGB3 (0.71) | ITGB3ITGA2BITGAV | |
| SCHEMBL8398958 | 0.70 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL8897339 | 0.69 | PRSS1 (0.34) | ITGB3ITGA2BITGAVF2PRSS1 | |
| SCHEMBL7402539 | 0.68 | ITGB3 (0.59) | ITGB3ITGA2BITGAVF2F10 | |
| SCHEMBL7401076 | 0.68 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2PRSS1 | |
| SCHEMBL8401294 | 0.67 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7395726 | 0.67 | ITGB3 (0.69) | ITGB3ITGA2BITGAVF2F10 | |
| SCHEMBL7397591 | 0.67 | ITGB3 (0.68) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |