Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074695 | 0.95 | LMNA (0.44) | LMNAALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL2078523 | 0.88 | ALDH1A1 (0.50) | LMNAALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL8897441 | 0.87 | TSHR (0.33) | LMNATSHRTDP1CYP3A4 | |
| SCHEMBL4611100 | 0.84 | LMNA (0.48) | LMNAALDH1A1TSHRTDP1CYP2D6 | |
| SCHEMBL28637129 | 0.82 | LMNA (0.31) | LMNATSHR | |
| SCHEMBL20298367 | 0.82 | ALDH1A1 (0.37) | LMNAALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL19511819 | 0.81 | LMNA (0.46) | LMNAALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL6261263 | 0.80 | TSHR (0.46) | LMNAALDH1A1TSHRTDP1CYP2D6 | |
| SCHEMBL29023675 | 0.79 | ALDH1A1 (0.52) | LMNAALDH1A1TSHR | |
| SCHEMBL15178124 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110954-A | Catalytic conversion to lactone | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| WO-1992000973-A1 | DEHYDROGENATION OF DIOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |