Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896541 | 0.88 | PTPN1 (0.72) | PTPN1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL6194328 | 0.85 | ATM (0.57) | PTPN1RXRAL3MBTL1MAPTTDP1 | |
| SCHEMBL19612388 | 0.82 | L3MBTL1 (0.67) | PTPN1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL23290166 | 0.82 | CCNB2 (0.50) | PTPN1L3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL1561432 | 0.81 | PPIA (0.53) | PTPN1L3MBTL1MAPTTDP1MAPK1 | |
| Acetic Acid SCHEMBL28238681 | 0.81 | RXRA (0.73) | PTPN1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL1115032 | 0.81 | PTPN1 (0.61) | PTPN1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL5339466 | 0.79 | PTPN1 (0.56) | PTPN1L3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL11734972 | 0.79 | HTT (0.69) | PTPN1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL29940577 | 0.79 | PTPN1 (0.68) | PTPN1L3MBTL1MAPTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712493-A4 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMA CORP (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0712493-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004277-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |