Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860972 | 0.87 | HCAR2 (0.53) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL9860987 | 0.87 | HCAR2 (0.53) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL9840734 | 0.87 | HCAR2 (0.53) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL34034 | 0.84 | THRB (0.46) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL8894317 | 0.83 | LMNA (0.47) | GAAKMT2AMEN1ALDH1A1LMNA | |
| Water SCHEMBL28126876 | 0.83 | THRB (0.45) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL9840743 | 0.83 | HCAR2 (0.61) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL12100901 | 0.82 | HCAR2 (0.42) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| Acrylic Acid SCHEMBL7185233 | 0.81 | THRB (0.44) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL8895270 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BGAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0045354-A1 | A method of dyeing and printing hydrophobic fibrous materials, and azo dyestuffs suitable therefor | CASSELLA Aktiengesellschaft (DE) | 1982-02-10 | — | — | EP | disclosed |