Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342866 | 0.79 | CA12 (0.34) | MAPK1 | |
| SCHEMBL9340766 | 0.78 | GRIA1 (0.34) | — | |
| SCHEMBL8896635 | 0.77 | — | — | |
| SCHEMBL10695874 | 0.75 | BCAT1 (0.34) | — | |
| SCHEMBL10695876 | 0.75 | BCAT1 (0.34) | — | |
| SCHEMBL7668488 | 0.75 | AR (0.33) | — | |
| SCHEMBL8914465 | 0.74 | BCAT1 (0.37) | — | |
| SCHEMBL8899124 | 0.73 | CHEK1 (0.38) | — | |
| SCHEMBL7955804 | 0.72 | L3MBTL1 (0.39) | — | |
| SCHEMBL7951685 | 0.72 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012884-A1 | HERBICIDAL 6-HETEROCYCLIC INDAZOLE DERIVATIVES | FMC CORPORATION (US) | 1997-04-10 | — | — | WO | disclosed |