Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951685 | 0.91 | L3MBTL1 (0.40) | L3MBTL1BCAT1BCAT2MAPK14TSHR | |
| SCHEMBL27482640 | 0.86 | BCAT2 (0.33) | BCAT1BCAT2ARGRM4 | |
| SCHEMBL29709206 | 0.83 | HSD11B1 (0.36) | L3MBTL1TSHRATMHCAR1GRM4 | |
| SCHEMBL7562176 | 0.83 | HSD11B1 (0.36) | L3MBTL1TSHRATMHCAR1GRM4 | |
| SCHEMBL31442537 | 0.83 | GRM4 (0.42) | GRM4 | |
| SCHEMBL8899310 | 0.82 | NPSR1 (0.36) | BCAT1BCAT2HTR1AADRA1BGLA | |
| SCHEMBL24241965 | 0.81 | MAP2K1 (0.35) | GRM4 | |
| SCHEMBL9114198 | 0.81 | ESR1 (0.40) | L3MBTL1ARGRM4 | |
| SCHEMBL7893270 | 0.81 | RXFP1 (0.46) | TSHRALDH1A1HPGDALOX15HTT | |
| SCHEMBL9338931 | 0.81 | ALDH1A1 (0.34) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | claimed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | claimed |
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | disclosed |