Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.50 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214706 | 0.81 | ALDH1A1 (0.88) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL9088587 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL8612042 | 0.73 | FOLH1 (0.52) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL8612045 | 0.73 | FOLH1 (0.52) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL24939480 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL2969312 | 0.72 | MMP9 (0.35) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15228983 | 0.72 | MMP9 (0.35) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9965337 | 0.70 | FOLH1 (1.00) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL17241614 | 0.70 | FOLH1 (1.00) | ALDH1A1LMNAMEN1KMT2AFOLH1 | |
| SCHEMBL23901487 | 0.70 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6025286-A | — | — | None | — | — | JP | disclosed |
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5430022-A | Endothelin antagonists; hypotensive agents; treatment for angina pectoris, brain disorders, asthma, renal failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| JP-H0625286-A | PEPTIDE COMPOUND | FUJISAWA PHARMACEUT CO LTD | 1994-02-01 | — | — | JP | disclosed |
| JP-H00625286-A | — | — | 0001-01-01 | — | — | JP | disclosed |