Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093600 | 0.74 | PTGS2 (0.53) | PTGS2CSF1RPTGS1 | |
| SCHEMBL8099800 | 0.74 | MAP4K4 (0.54) | PTGS2CSF1RPTGS1 | |
| Carbamic Acid SCHEMBL11786852 | 0.69 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6050626 | 0.67 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6470141 | 0.67 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL7395459 | 0.67 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL29812023 | 0.66 | DHODH (0.44) | — | |
| SCHEMBL29812284 | 0.66 | LMNA (0.44) | CSF1R | |
| SCHEMBL6622488 | 0.66 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL1572913 | 0.66 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |