SCHEMBL8897918

SCHEMBL8897918

OC(=S)NN1CCNCC1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.38
GNAO1 P09471 2/20 0.38
GNAI1 P63096 2/20 0.38
HSD17B10 Q99714 1/20 0.36
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
ABCC1 P33527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28468503 0.93 GNAI3 (0.35) GNAI3GNAO1GNAI1HSD17B10
SCHEMBL28754064 0.91 GNAI3 (0.34) GNAI3GNAO1GNAI1HSD17B10
Pyrrolidine SCHEMBL11631842 0.84 ALDH1A1 (0.33) CA2
Piperidine SCHEMBL11695430 0.82 ALDH1A1 (0.38) CA2
Morpholine SCHEMBL11628791 0.79 CA12 (0.52) CA12CA1CA2CA9
SCHEMBL1132836 0.78 GNAI3 (0.37) GNAI3GNAO1GNAI1HSD17B10CA12
SCHEMBL4436078 0.78 HSD17B10 (0.48) GNAI3GNAO1GNAI1HSD17B10CA12
Piperidine SCHEMBL28394461 0.78 ALDH1A1 (0.33) CA2
SCHEMBL28754062 0.76 CA2 (0.54) GNAI3GNAO1GNAI1HSD17B10CA12
SCHEMBL14844194 0.76 CA2 (0.54) GNAI3GNAO1GNAI1HSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997003073-A1 THIAZOLYL TRIAZOLOTHIAZOLE DERIVATIVES YUNGJIN PHARMACEUTICAL CO., LTD. (KR) 1997-01-30 WO disclosed