Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL11631835 | 0.85 | CA2 (0.38) | GNAI3GNAO1GNAI1CA2CA12 | |
| Piperidine SCHEMBL11695417 | 0.83 | CA2 (0.41) | GNAI3GNAO1GNAI1CA2CHKA | |
| Morpholine SCHEMBL11628785 | 0.80 | CA12 (0.41) | CA2CA12CA1CA9KDM4E | |
| SCHEMBL10403133 | 0.78 | GNAI3 (0.46) | GNAI3GNAO1GNAI1CA2CA12 | |
| SCHEMBL3267951 | 0.78 | GNAI3 (0.46) | GNAI3GNAO1GNAI1CA2CA12 | |
| SCHEMBL3074805 | 0.77 | — | — | |
| SCHEMBL4823917 | 0.76 | GNAI3 (0.44) | GNAI3GNAO1GNAI1CA2CA12 | |
| SCHEMBL4436078 | 0.76 | HSD17B10 (0.48) | GNAI3GNAO1GNAI1CA2CA12 | |
| SCHEMBL1394575 | 0.76 | GNAI3 (0.49) | GNAI3GNAO1GNAI1CA2CA12 | |
| SCHEMBL1459326 | 0.76 | GNAI3 (0.44) | GNAI3GNAO1GNAI1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003073-A1 | THIAZOLYL TRIAZOLOTHIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |