Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 14/20 | 0.55 |
| ▸ | NPY1R | P25929 | 6/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AQP1 | P29972 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901000 | 1.00 | ACACB (0.59) | ACACBNPY5RNPY1RTBXA2RACACA | |
| SCHEMBL6039406 | 0.92 | ACACB (0.69) | ACACBNPY5RNPY1RTBXA2RACACA | |
| SCHEMBL6039411 | 0.92 | ACACB (0.69) | ACACBNPY5RNPY1RTBXA2RACACA | |
| SCHEMBL8897974 | 0.82 | ACACB (0.58) | ACACBNPY5RNPY1RACACA | |
| SCHEMBL8897971 | 0.82 | ACACB (0.58) | ACACBNPY5RNPY1RACACA | |
| SCHEMBL13590697 | 0.80 | ACACB (0.60) | ACACBNPY5RNPY1RACACA | |
| SCHEMBL8891919 | 0.79 | CA12 (0.52) | ACACBNPY5RTBXA2R | |
| SCHEMBL8899787 | 0.78 | TGFBR1 (0.64) | NPY5RNPY1RMAPT | |
| SCHEMBL13590690 | 0.77 | ACACB (0.57) | ACACBNPY5RNPY1RACACAALDH1A1 | |
| SCHEMBL8900540 | 0.77 | NPY5R (0.53) | ACACBNPY5RTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |