Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900151 | 1.00 | ICMT (0.52) | ICMTALBL3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL8900123 | 0.99 | ICMT (0.50) | ICMTALBL3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL8899562 | 0.95 | HDAC6 (0.49) | ICMTALBL3MBTL1ALDH1A1 | |
| SCHEMBL7615671 | 0.90 | TRPV1 (0.50) | ALDH1A1 | |
| SCHEMBL9781730 | 0.87 | L3MBTL1 (0.50) | L3MBTL1CETP | |
| SCHEMBL9359520 | 0.83 | — | — | |
| SCHEMBL8900211 | 0.82 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1CETP | |
| SCHEMBL9781699 | 0.80 | L3MBTL1 (0.51) | L3MBTL1CETP | |
| SCHEMBL9775331 | 0.78 | L3MBTL1 (0.49) | L3MBTL1CETP | |
| SCHEMBL25276969 | 0.78 | CA12 (0.64) | ICMTALBEPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777471-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |