SCHEMBL8900211

SCHEMBL8900211

CCCCCN(OCc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.52
CETP P11597 3/20 0.50
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27078358 0.89 ALOX5 (0.47) L3MBTL1CETPALDH1A1CYP3A4TSHR
SCHEMBL9781699 0.85 L3MBTL1 (0.51) L3MBTL1CETP
SCHEMBL23616321 0.84 L3MBTL1 (0.49) L3MBTL1CETPALDH1A1CYP3A4TSHR
SCHEMBL9781730 0.84 L3MBTL1 (0.50) L3MBTL1CETP
SCHEMBL27345618 0.83 L3MBTL1 (0.46) L3MBTL1CETP
SCHEMBL8900123 0.83 ICMT (0.50) L3MBTL1ALDH1A1
SCHEMBL8899583 0.83 L3MBTL1 (0.76) L3MBTL1
SCHEMBL9775331 0.83 L3MBTL1 (0.49) L3MBTL1CETP
SCHEMBL10761433 0.83 L3MBTL1 (0.51) L3MBTL1
SCHEMBL9781776 0.82 L3MBTL1 (0.78) L3MBTL1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777471-A1 INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-06-11 EP disclosed
WO-1996003983-A1 INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-15 WO disclosed