Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472860 | 0.98 | HTR7 (0.43) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8473694 | 0.95 | KDM4E (0.44) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8477346 | 0.94 | KDM4E (0.45) | CNR2KDM4EALDH1A1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL8472609 | 0.89 | KDM4E (0.43) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8475143 | 0.88 | CNR2 (0.51) | CNR2ALDH1A1 | |
| SCHEMBL8472179 | 0.87 | KDM4E (0.48) | CNR2KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL8477838 | 0.87 | CNR2 (0.48) | CNR2KDM4EALDH1A1ABCB1HTR7 | |
| Hydrochloric Acid SCHEMBL8473198 | 0.87 | KDM4E (0.46) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8472493 | 0.87 | KDM4E (0.52) | CNR2KDM4EALDH1A1LMNAHTR7 | |
| SCHEMBL8473412 | 0.87 | LTA4H (0.51) | KDM4EALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |