Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 6/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962986 | 0.81 | PTGDR2 (0.41) | PTGDR2TRPV4 | |
| SCHEMBL8177205 | 0.80 | CA1 (0.46) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL523615 | 0.77 | AR (0.49) | GAA | |
| SCHEMBL31726528 | 0.76 | TRPV4 (0.43) | CA1CA2CA9PTGDR2TRPV4 | |
| SCHEMBL11890400 | 0.74 | TRPV4 (0.51) | PTGDR2TRPV4GAA | |
| SCHEMBL8897228 | 0.74 | STS (0.49) | CA1CA2CA9STSGAA | |
| SCHEMBL16772773 | 0.73 | AR (0.36) | PTGDR2TRPV4GAA | |
| SCHEMBL4880333 | 0.72 | CA2 (0.49) | CA1CA2CA9CA12GAA | |
| SCHEMBL18528835 | 0.71 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL13377029 | 0.70 | CYP2A6 (0.41) | CA1CA2CA9PTGDR2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044314-A1 | N-ACYL SULFAMIC ACID ESTERS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |