Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636272 | 1.00 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL4054427 | 1.00 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL13267741 | 1.00 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL13267739 | 1.00 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL13509014 | 0.98 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL128911 | 0.91 | TDP1 (0.43) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL8039193 | 0.88 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL31300438 | 0.88 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL28393903 | 0.88 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL28399899 | 0.88 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644195-B2 | Compounds and methods for purification of serine proteases | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9200268-B2 | Compounds and methods for purification of serine proteases | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150337285-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) | 2015-11-26 | — | — | US | disclosed |
| US-20140346397-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) | 2014-11-27 | — | — | US | disclosed |
| US-20140186923-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
| EP-0531715-B1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5426237-A | Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0531715-A1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337285-A1 | COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES | PRSS1, HPN, PRSS8 | KDM4C 2833/4885KDM4A 3256/4885PHF8 3329/4885 |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | KDM4C 4172/4885KDM4A 4236/4885PHF8 3940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.