SCHEMBL889908

SCHEMBL889908

Cc1ccc2ccc(S(=O)(=O)O)cc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.62
CYP2A6 P11509 4/20 0.56
CYP1A2 P05177 4/20 0.56
ALDH1A1 P00352 6/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
HSD17B10 Q99714 2/20 0.51
TSHR P16473 2/20 0.51
USP2 O75604 1/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 1/20 0.49
CASP6 P55212 1/20 0.49
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27794185 0.98 SNCA (0.60) SNCACYP2A6CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL15851428 0.94 SNCA (0.65) SNCACYP2A6CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL4075108 0.94 SNCA (0.69) SNCACYP2A6CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL10604074 0.92 SNCA (0.67) SNCACYP2A6CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL29574227 0.87 ALDH1A1 (0.59) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL822307 0.87 ALDH1A1 (0.59) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL29381755 0.87 ALDH1A1 (0.59) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL3825262 0.85 ALDH1A1 (0.57) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR
Hydrochloric Acid SCHEMBL11162227 0.85 ALDH1A1 (0.57) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR
Ammonia Solution, Strong SCHEMBL10613938 0.85 ALDH1A1 (0.57) SNCAALDH1A1SMN1; SMN2HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP claimed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US claimed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP claimed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO claimed
US-10022996-B2 Infrared sensitive color-forming composition, infrared curable color-forming composition, lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2018-07-17 US disclosed
US-20180154671-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE-MAKING METHOD FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
EP-3127928-B1 POLYMER COMPOUND, POSITIVE RESIST COMPOSITION, LAMINATE, AND RESIST PATTERNING PROCESS SHINETSU CHEMICAL CO (JP) 2017-11-15 EP disclosed
US-9707749-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2017-07-18 US disclosed
US-20170123315-A1 COLOR DEVELOPING COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR, PLATE MAKING METHOD FOR LITHOGRAPHIC PRINTING PLATE, AND COLOR DEVELOPER FUJIFILM CORPORATION (JP) 2017-05-04 US disclosed
EP-3127928-A1 POLYMER COMPOUND, POSITIVE RESIST COMPOSITION, LAMINATE, AND RESIST PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-08 EP disclosed
US-20170017157-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2017-01-19 US disclosed
US-9529261-B2 Color-forming composition, color-forming curable composition, lithographic printing plate precursor and plate making method, and color-forming compound FUJIFILM CORPORATION (JP) 2016-12-27 US disclosed
US-20110045408-A1 Color-forming photosensitive composition, lithographic printing plate precursor and novel cyanine dye FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed
US-20100227390-A1 Ethanol Water Solution Concentrating Device HONDA MOTOR CO., LTD. (JP) 2010-09-09 US disclosed
US-7351808-B2 Anionic monoazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-01 US disclosed
US-7351808-B2 Anionic monoazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-01 US disclosed
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP disclosed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US disclosed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP disclosed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110045408-A1 Color-forming photosensitive composition, lithographic printing plate precursor and novel cyanine dye MAP1LC3A, MAP1LC3C, MAP1LC3B SNCA 4491/4885CYP2A6 1527/4885CYP1A2 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.