Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897690 | 0.88 | CYP11B2 (0.51) | CYP11B1CYP11B2MAOARAB9AKDM4E | |
| SCHEMBL8899803 | 0.73 | CYP11B2 (0.31) | CYP11B2KDM4EALDH1A1AR | |
| SCHEMBL28062885 | 0.72 | EGFR (0.46) | DYRK3PIM1MAPK8MAPK9MAPK10 | |
| SCHEMBL5527743 | 0.72 | MCHR1 (0.46) | CYP11B1CYP11B2MAOARAB9AKDM4E | |
| SCHEMBL29891682 | 0.72 | MCHR1 (0.46) | CYP11B1CYP11B2MAOARAB9AKDM4E | |
| SCHEMBL8898217 | 0.71 | SIRT2 (0.38) | CYP11B2MAPTPIM1DYRK1APIM3 | |
| SCHEMBL25389422 | 0.70 | GSK3B (0.45) | CYP11B1CYP11B2MAOARAB9AKDM4E | |
| SCHEMBL1921296 | 0.69 | KDM4E (0.53) | KDM4EHCRTR1MAPTCASP1CASP7 | |
| SCHEMBL8900309 | 0.69 | CYP11B2 (0.37) | CYP11B1CYP11B2MAOARAB9AKDM4E | |
| SCHEMBL1605933 | 0.68 | CYP11B2 (0.82) | CYP11B1CYP11B2MAOAKDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |