SCHEMBL1921296

SCHEMBL1921296

Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
MAPT P10636 3/20 0.53
HCRTR1 O43613 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
PTGER4 P35408 1/20 0.44
GPR3 P46089 1/20 0.44
HTR6 P50406 1/20 0.44
BAZ2B Q9UIF8 1/20 0.44
KCNH2 Q12809 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PSMB8 P28062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979911 0.95 KDM4E (0.50) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL24611600 0.89 BCHE (0.47) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL1921474 0.89 GPR3 (0.64) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL14050151 0.88 BCHE (0.56) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL13899688 0.83 MAPK8 (0.46) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL4130418 0.83 KDM4E (0.42) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL4117448 0.82 KDM4E (0.51) KDM4EMAPTBAZ2BKCNH2ALDH1A1
SCHEMBL2183525 0.82 KDM4E (0.41) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL9979914 0.81 MAT2A (0.49) KDM4EMAPTHCRTR1CASP1CASP7
SCHEMBL21782165 0.81 RAB9A (0.55) KDM4EMAPTHCRTR1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11411185-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2022-08-09 US disclosed
US-10314816-B2 Antimicrobial compounds, compositions and methods of use thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-11 US disclosed
WO-2017044569-A1 HETEROCYCLIC CONSTRAINED TRICYCLIC SULFONAMIDES AS ANTI-CANCER AGENTS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2017-03-16 WO disclosed
US-20160248025-A1 Organic Electroluminescent Device UDC IRELAND LTD (IE) 2016-08-25 US disclosed
US-20160248025-A1 Organic Electroluminescent Device UDC IRELAND LTD (IE) 2016-08-25 US disclosed
US-9359548-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2016-06-07 US disclosed
US-9359548-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2016-06-07 US disclosed
US-9133115-B2 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication ACHILLION PHARMACEUTICALS, INC. (US) 2015-09-15 US disclosed
US-20140113890-A1 NEW 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION ACHILLION PHARMACEUTICALS, INC. (US) 2014-04-24 US disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
US-20100084967-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-04-08 US disclosed
US-20100084967-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-04-08 US disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20080286605-A1 efficiency (electric power consumption) and durability; complex is chemical stability FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080286605-A1 efficiency (electric power consumption) and durability; complex is chemical stability FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10314816-B2 Antimicrobial compounds, compositions and methods of use thereof CLPP, ATP5ME, PCNA KDM4E 4409/4885MAPT 4759/4885HCRTR1 4618/4885
US-20140113890-A1 NEW 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION ZC3HAV1, VIP, ZC3HAV1L KDM4E 556/4885MAPT 4391/4885HCRTR1 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.