Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181148 | 0.87 | FFAR4 (0.39) | CHRM4DRD1FFAR4IDO1ADORA2A | |
| SCHEMBL8901365 | 0.73 | HPGD (0.43) | — | |
| SCHEMBL6182187 | 0.73 | IDO1 (0.32) | CHRM4FFAR4IDO1CTNNB1WNT3A | |
| SCHEMBL9118552 | 0.71 | ACVRL1 (0.43) | CTNNB1WNT3ADRD2HTR2A | |
| SCHEMBL6182417 | 0.70 | SCN9A (0.33) | IDO1CXCR2SMYD3 | |
| SCHEMBL30971751 | 0.70 | ADORA2A (0.41) | CHRM4DRD1FFAR4IDO1ADORA2A | |
| SCHEMBL27470782 | 0.70 | ADORA2A (0.41) | CHRM4DRD1FFAR4IDO1ADORA2A | |
| SCHEMBL8884156 | 0.69 | IDO1 (0.37) | CHRM4FFAR4IDO1ADORA2ACXCR2 | |
| SCHEMBL8886611 | 0.69 | PDK2 (0.39) | FFAR4IDO1ADORA2ACTNNB1WNT3A | |
| SCHEMBL6184733 | 0.68 | HSD17B10 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |