Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183171 | 0.81 | MTNR1A (0.40) | ACVRL1CTNNB1WNT3AMT-CO2KDM4E | |
| SCHEMBL6076958 | 0.80 | ACVRL1 (0.44) | ACVRL1CTNNB1WNT3AKDM4CMT-CO2 | |
| SCHEMBL8231095 | 0.80 | HDAC3 (0.49) | CTNNB1WNT3AKDM4CMT-CO2KDM4E | |
| SCHEMBL9239223 | 0.78 | MTNR1A (0.38) | ACVRL1KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL636844 | 0.77 | CTNNB1 (0.46) | CTNNB1WNT3AKDM4CMT-CO2KDM4E | |
| SCHEMBL6181148 | 0.77 | FFAR4 (0.39) | CTNNB1WNT3ANPSR1DRD2HTR2A | |
| SCHEMBL6184460 | 0.77 | MTNR1A (0.38) | ACVRL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6077935 | 0.76 | KDM4E (0.43) | ACVRL1KDM4CMT-CO2KDM4EPOLB | |
| SCHEMBL22886786 | 0.75 | MGAM (0.49) | CTNNB1WNT3AMT-CO2KDM4EHDAC3 | |
| SCHEMBL6182096 | 0.75 | AOC3 (0.39) | ACVRL1KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |