Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476333 | 0.94 | KDM4E (0.49) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8477583 | 0.93 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472285 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8471992 | 0.93 | KMT2A (0.47) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472581 | 0.92 | KDM4E (0.46) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472597 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8899446 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8476916 | 0.88 | KDM4E (0.43) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8477752 | 0.88 | HPGD (0.46) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8477279 | 0.87 | LMNA (0.51) | ALDH1A1KDM4EMAPK1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |