Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472213 | 0.99 | KDM4E (0.53) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL8472229 | 0.96 | KDM4E (0.55) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL8476848 | 0.95 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL8899446 | 0.93 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2HPGDALOX15 | |
| SCHEMBL8472597 | 0.92 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HPGDALOX15 | |
| SCHEMBL8474454 | 0.90 | LMNA (0.53) | ALDH1A1KDM4ESMN1; SMN2POLBKMT2A | |
| SCHEMBL8475956 | 0.89 | KDM4E (0.54) | ALDH1A1KDM4EPOLBHPGDHSD17B10 | |
| SCHEMBL8472285 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2HPGDALOX15 | |
| SCHEMBL8472493 | 0.89 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL8476333 | 0.88 | KDM4E (0.49) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |