Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 11/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661851 | 0.98 | FDPS (0.42) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL11662678 | 0.98 | FDPS (0.42) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL29135504 | 0.98 | FDPS (0.42) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL11664072 | 0.93 | — | — | |
| SCHEMBL11660695 | 0.82 | — | — | |
| SCHEMBL15333380 | 0.78 | FDPS (0.45) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL11429363 | 0.78 | FDPS (0.41) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL15333382 | 0.78 | FDPS (0.45) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL294887 | 0.76 | ALOX15 (0.52) | FDPSGGPS1 | |
| SCHEMBL7610539 | 0.76 | FDPS (0.43) | FDPSGGPS1SMPD1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675031-A | 4-hydroxy-2-cyclopentenone derivatives and anticancer agent and bone formation accelerator containing the same | TEIJIN LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0448726-B1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0659728-A1 | 4-HYDROXY-2-CYCLOPENTENONE DERIVATIVE AND CARCINOSTATIC AND OSTEOGENESIS PROMOTER CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338844-A | 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient | TEIJIN LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0448726-A1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1991-10-02 | — | — | EP | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |