Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.50 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901937 | 0.82 | MAPT (0.55) | MAPTSMN1; SMN2ANO1ANO2ALDH1A1 | |
| SCHEMBL8899897 | 0.82 | MRGPRX4 (0.57) | MAPTSMN1; SMN2ANO1ANO2ALDH1A1 | |
| SCHEMBL8898815 | 0.80 | TSHR (0.59) | MAPTSMN1; SMN2HPGDTSHRLMNA | |
| SCHEMBL25202091 | 0.78 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1POLBKDM4E | |
| SCHEMBL8899650 | 0.74 | PDE4D (0.60) | MAPTSMN1; SMN2POLBKDM4EUSP2 | |
| SCHEMBL2090476 | 0.73 | KMT2A (0.57) | MAPTSMN1; SMN2ALDH1A1POLBTSHR | |
| SCHEMBL413085 | 0.72 | TACR2 (0.78) | MAPTSMN1; SMN2TACR2ALDH1A1HPGD | |
| SCHEMBL31544508 | 0.72 | ALDH1A1 (0.52) | MAPTSMN1; SMN2TACR2ALDH1A1HPGD | |
| SCHEMBL31544516 | 0.72 | ALDH1A1 (0.52) | MAPTSMN1; SMN2TACR2ALDH1A1HPGD | |
| SCHEMBL7784719 | 0.70 | PDCD1 (0.74) | MAPTSMN1; SMN2TACR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |