Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | CASP6 | P55212 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692623 | 0.86 | TDP1 (0.63) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL458 | 0.83 | CASP6 (0.62) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL29401731 | 0.83 | CASP6 (0.62) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL1740621 | 0.81 | CASP6 (0.61) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL28582319 | 0.81 | CTSB (0.61) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL1740623 | 0.81 | CASP6 (0.61) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL15302617 | 0.81 | TDP1 (0.50) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL12192902 | 0.79 | CASP6 (0.57) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL7806886 | 0.79 | CASP6 (0.57) | KDM4EMEN1MAPTKMT2APKM | |
| SCHEMBL2111476 | 0.78 | MAPT (1.00) | KDM4EMEN1MAPTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486470-B1 | An aromatic substituted glycoside | HOECHST CELANESE CORP (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0263435-B1 | An aromatic substituted glycoside | HOECHST CELANESE CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5320954-A | Enzymatic glucosylation with cyclodextrins; substrate for determining amylase | HOECHST CELANESE CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-5158872-A | Amalyase analysis | HOECHST CELANESE CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0486470-A1 | An aromatic substituted glycoside | HOECHST CELANESE CORPORATION (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4963479-A | INCLUDING BUFFER AND ENZYME ACTIVATOR | HOECHST CELANESE CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0263435-A2 | An aromatic substituted glycoside | HOECHST CELANESE CORPORATION (US) | 1988-04-13 | — | — | EP | disclosed |