Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | AQP1 | P29972 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900115 | 0.88 | NPY5R (0.46) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8899118 | 0.87 | NPY5R (0.45) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8890893 | 0.80 | NPY5R (0.44) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8891562 | 0.80 | NPY5R (0.46) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8898927 | 0.78 | NPY5R (0.49) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8898901 | 0.78 | NPY5R (0.49) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8891551 | 0.76 | VCP (0.54) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8899106 | 0.75 | VCP (0.53) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8901221 | 0.74 | DCPS (0.51) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 | |
| SCHEMBL8891992 | 0.74 | PRKCQ (0.41) | NPY5RMCHR1ADRA2AAQP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |