Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 4/20 | 0.41 |
| ▸ | VCP | P55072 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | AQP1 | P29972 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891976 | 0.86 | VCP (0.52) | VCP | |
| SCHEMBL8900115 | 0.85 | NPY5R (0.46) | PRKCQVCPNPY5RAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8899118 | 0.84 | NPY5R (0.45) | PRKCQVCPNPY5RAQP1ALDH1A1 | |
| SCHEMBL8901221 | 0.83 | DCPS (0.51) | PRKCQVCPNPY5RAQP1ALDH1A1 | |
| SCHEMBL8891562 | 0.75 | NPY5R (0.46) | VCPNPY5RAQP1ALDH1A1MAPT | |
| SCHEMBL8898901 | 0.74 | NPY5R (0.49) | NPY5RAQP1ALDH1A1MAPTADRA2A | |
| SCHEMBL8900065 | 0.74 | NPY5R (0.43) | PRKCQNPY5RAQP1ALDH1A1MAPT | |
| SCHEMBL8891551 | 0.74 | VCP (0.54) | VCPNPY5RAQP1ALDH1A1MAPT | |
| SCHEMBL8900965 | 0.73 | APP (0.47) | PRKCQVCPNPY5RAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8899106 | 0.73 | VCP (0.53) | VCPNPY5RAQP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |