Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898151 | 0.86 | CYP3A4 (0.43) | PARP1CXCR5HTTMEN1NR1I2 | |
| SCHEMBL8897692 | 0.83 | PARP1 (0.33) | KDM4EPARP1HTTMEN1NR1I2 | |
| SCHEMBL8900078 | 0.82 | KDM4E (0.38) | KDM4EPARP1HTTMEN1NR1I2 | |
| SCHEMBL8896415 | 0.81 | PARP1 (0.35) | KDM4EPARP1CXCR5HTTMEN1 | |
| SCHEMBL8899737 | 0.80 | PARP1 (0.35) | KDM4EPARP1CXCR5HTTMEN1 | |
| SCHEMBL8901079 | 0.75 | TLR8 (0.33) | KDM4EMEN1LMNAKMT2A | |
| SCHEMBL8896377 | 0.72 | LMNA (0.33) | KDM4EMEN1LMNAKMT2A | |
| SCHEMBL6515634 | 0.70 | KAT8 (0.46) | KDM4EPARP1MAPT | |
| SCHEMBL8089369 | 0.67 | GABRA1 (0.42) | KDM4EPARP1HTTMEN1NR1I2 | |
| SCHEMBL8898159 | 0.67 | CYP3A4 (0.42) | PARP1HTTMEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703091-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |