Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055026 | 0.84 | MAPT (0.38) | ALDH1A1GAAMAPTPTPN1PTPRC | |
| SCHEMBL18440342 | 0.83 | CES1 (0.39) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL27546304 | 0.76 | PTPN1 (0.44) | PTPN1PTPRCPTPRFCDC25BCYP2A6 | |
| SCHEMBL11574438 | 0.75 | SIGMAR1 (0.38) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL16339665 | 0.74 | PTPN1 (0.46) | ALDH1A1GAAMAPTL3MBTL1PTPN1 | |
| SCHEMBL30588920 | 0.71 | ESR2 (0.53) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL11624145 | 0.71 | ESR2 (0.53) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL13735951 | 0.71 | CYP1A2 (0.44) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL11025928 | 0.71 | SRD5A1 (0.37) | NPC1RAB9AALDH1A1GAAKDM4E | |
| SCHEMBL16393502 | 0.71 | HTR6 (0.37) | PTPN1PTPRCPTPRFCDC25BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017332-A1 | 1-ARYLSULPHONYL, ARYL(THIO)CARBONYL PYRIDAZINO DERIVATIVES AND METHODS OF PREPARATION | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |