SCHEMBL4055026

SCHEMBL4055026

C1=C2c3ccccc3CC2CCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
CYP19A1 P11511 1/20 0.36
ACHE P22303 2/20 0.35
NOS3 P29474 4/20 0.35
NOS2 P35228 3/20 0.35
PTPN1 P18031 2/20 0.35
PTPRC P08575 1/20 0.34
PTPRF P10586 1/20 0.34
CDC25B P30305 1/20 0.34
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
CHRNA7 P36544 1/20 0.32
METAP1 P53582 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8900291 0.84 NPC1 (0.39) MAPTCYP19A1NOS3NOS2PTPN1
SCHEMBL18440342 0.73 CES1 (0.39) MAPTCYP19A1NOS3NOS2PTPN1
SCHEMBL27546304 0.73 PTPN1 (0.44) ACHEPTPN1PTPRCPTPRFCDC25B
SCHEMBL16339665 0.72 PTPN1 (0.46) MAPTACHEPTPN1PTPRCPTPRF
SCHEMBL15217970 0.69 MAOA (0.32) ALDH1A1
SCHEMBL16393502 0.68 HTR6 (0.37) ACHENOS3NOS2PTPN1PTPRC
SCHEMBL4082366 0.68 TSHR (0.39) CYP19A1ACHENOS3NOS2PTPN1
SCHEMBL2419305 0.68 ESR2 (0.63) CYP19A1ACHEPTPN1PTPRCPTPRF
SCHEMBL11615530 0.67 HTR1A (0.40) ACHETSHRCHRNA7METAP1
SCHEMBL2958443 0.67 NPSR1 (0.34) TSHRSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997017332-A1 1-ARYLSULPHONYL, ARYL(THIO)CARBONYL PYRIDAZINO DERIVATIVES AND METHODS OF PREPARATION ORTHO PHARMACEUTICAL CORPORATION (US) 1997-05-15 WO claimed
US-11981773-B2 Ring-opened copolymer ZEON CORPORATION (JP) 2024-05-14 US disclosed
WO-2023189497-A1 COPOLYMER, RUBBER COMPOSITION AND CROSSLINKED RUBBER 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023189496-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT 日本ゼオン株式会社 2023-10-05 WO disclosed
US-11718709-B2 Ring-opening copolymer composition ZEON CORPORATION (JP) 2023-08-08 US disclosed
EP-3276632-B1 DIELECTRIC FILM, AND FILM CAPACITOR, CONNECTIVE CAPACITOR, INVERTER, AND ELECTRIC VEHICLE EACH INCLUDING SAME KYOCERA CORP (JP) 2023-06-07 EP disclosed
US-20230060226-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION ZEON CORPORATION (JP) 2023-03-02 US disclosed
CN-111133026-B Liquid cyclopentene ring-opening polymer, rubber composition, and rubber crosslinked product 日本瑞翁株式会社 2023-02-17 CN disclosed
CN-111094384-B Liquid cyclopentene ring-opening copolymer, crosslinkable composition, and crosslinked rubber 日本瑞翁株式会社 2023-02-17 CN disclosed
EP-3533829-B1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2021-11-24 EP disclosed
WO-2021153417-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION 日本ゼオン株式会社 2021-08-05 WO disclosed
WO-2021107041-A1 CYCLIC OLEFIN POLYMER, METHOD FOR PRODUCING SAME, AND OPTICAL ELEMENT 日本ゼオン株式会社 2021-06-03 WO disclosed
WO-2021060418-A1 CYCLIC POLYMER HYDRIDE, MANUFACTURING METHOD THEREFOR, AND RESIN COMPOSITION 日本ゼオン株式会社 2021-04-01 WO disclosed
WO-2020195801-A1 RING-OPENING POLYMER HYDRIDE, RESIN COMPOSITION, AND MOLDED ARTICLE 日本ゼオン株式会社 2020-10-01 WO disclosed
WO-2020085306-A1 METAL-OXO COMPLEX AND METHOD FOR PRODUCTION THEREOF RIMTEC株式会社 2020-04-30 WO disclosed
WO-2020036001-A1 COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOOLEFIN, PRODUCTION METHOD THEREFOR, RUBBER COMPOSITION, AND CROSSLINKED RUBBER OBJECT 日本ゼオン株式会社 2020-02-20 WO disclosed
US-20190169360-A1 CROSSLINKED RUBBER ZEON CORPORATION (JP) 2019-06-06 US disclosed
EP-3276632-A1 DIELECTRIC FILM, AND FILM CAPACITOR, CONNECTIVE CAPACITOR, INVERTER, AND ELECTRIC VEHICLE EACH INCLUDING SAME Kyocera Corporation (JP) 2018-01-31 EP disclosed
US-20090143523-A1 Cycloolefin additon polymer, composite material and molded article thereof, and optical material ZEON CORPORATION (JP) 2009-06-04 US disclosed
EP-1652885-B1 POLYMERIZABLE COMPOSITION AND FORMED ARTICLE USING THE SAME ZEON CORP (JP) 2009-03-11 EP disclosed