Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096742 | 1.00 | TSHR (0.32) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| Bicarbonate SCHEMBL8900312 | 0.76 | ALDH1A1 (0.42) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL15842404 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL15842403 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL23255851 | 0.71 | FFAR3 (0.35) | TSHRALDH1A1RECQL | |
| SCHEMBL8161329 | 0.71 | FFAR3 (0.35) | TSHRALDH1A1RECQL | |
| SCHEMBL1683511 | 0.71 | FFAR3 (0.35) | TSHRALDH1A1RECQL | |
| SCHEMBL7794325 | 0.70 | ALDH1A1 (0.50) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL1270866 | 0.69 | TSHR (0.30) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL1270865 | 0.69 | TSHR (0.30) | TSHRALDH1A1ALOX15RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5521160-A | COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY | HOFFMANN-LA ROCHE INC. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |