Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.67 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MERTK | Q12866 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8891019 | 0.99 | SLC2A1 (0.70) | NPY5RSLC2A1RAD52USP2TSHR | |
| SCHEMBL2583768 | 0.82 | RAD52 (0.71) | SLC2A1RAD52USP2TSHRHTT | |
| SCHEMBL9776834 | 0.82 | SLC2A1 (0.97) | NPY5RSLC2A1HTTMAPTKDM4E | |
| SCHEMBL8899168 | 0.82 | ABCG2 (0.72) | NPY5RMAPTABCG2MEN1KMT2A | |
| SCHEMBL3583927 | 0.81 | ROCK2 (0.58) | NPY5RRAD52USP2TSHRHTT | |
| SCHEMBL10031967 | 0.81 | RAD52 (0.98) | SLC2A1RAD52USP2TSHRHTT | |
| SCHEMBL16404475 | 0.81 | NPY5R (0.70) | NPY5RSLC2A1MAPTKDM4EABCG2 | |
| SCHEMBL2591063 | 0.81 | NPY5R (1.00) | NPY5RSLC2A1TSHRHTTABCG2 | |
| Hydrochloric Acid SCHEMBL9776848 | 0.81 | SLC2A1 (1.00) | NPY5RSLC2A1HTTMAPTKDM4E | |
| SCHEMBL20149731 | 0.81 | NPC1 (0.73) | SLC2A1RAD52USP2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |