SCHEMBL8900410

SCHEMBL8900410

Cc1ccc2c(c1)C(C)CCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
HTR2C P28335 6/20 0.38
HTR2B P41595 5/20 0.38
SLC6A4 P31645 2/20 0.38
HTR2A P28223 5/20 0.38
LMNA P02545 1/20 0.38
ADRB1 P08588 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CNR1 P21554 1/20 0.38
SLC6A2 P23975 1/20 0.38
HRH1 P35367 1/20 0.38
KCNH2 Q12809 1/20 0.38
DRD2 P14416 1/20 0.37
DRD1 P21728 1/20 0.37
UGT2B17 O75795 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30298336 0.88 ACHE (0.43) ACHEHTR2CHTR2BSLC6A4HTR2A
SCHEMBL409985 0.88 ACHE (0.43) ACHEHTR2CHTR2BSLC6A4HTR2A
SCHEMBL6902991 0.85 SRD5A1 (0.42) ACHEHTR2CHTR2BSLC6A4HTR2A
SCHEMBL10283629 0.79 UGT2B17 (0.56) ACHELMNADRD2DRD1UGT2B17
SCHEMBL24593660 0.79 HTR2A (0.60) HTR2CHTR2BSLC6A4HTR2ALMNA
SCHEMBL24593626 0.79 HTR2A (0.60) HTR2CHTR2BSLC6A4HTR2ALMNA
SCHEMBL16543142 0.79 ACHE (0.51) ACHEHTR2CHTR2BSLC6A4LMNA
SCHEMBL22417595 0.79 UGT2B17 (0.56) ACHELMNADRD2DRD1UGT2B17
SCHEMBL4981817 0.79 ESR1 (0.46) SLC6A4LMNAHTR1ASLC6A2
SCHEMBL23239989 0.79 LMNA (0.37) HTR2CHTR2BSLC6A4LMNADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929328-B Composite ink and preparation method and device thereof TCL科技集团股份有限公司 2021-10-22 CN claimed
US-5396007-A Dehydrogenating dimethyltetrahydronaphthalene in diluted medium using palladium or platinum catalyst supported by activated carbon MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-03-07 US claimed
JP-9241183-A None JP disclosed
EP-3347342-B1 METHOD FOR THE PREPARATION OF BIGUANIDINE SALTS AND S-TRIAZINES BAYER CROPSCIENCE AG (DE) 2019-04-24 EP disclosed
WO-2017034872-A1 INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS JANSSEN PHARMACEUTICA NV (BE) 2017-03-02 WO disclosed
JP-H09241183-A PRODUCTION OF 1,5-DIMETHYLTETRALIN TEIJIN LTD 1997-09-16 JP disclosed
EP-0589490-B1 Dimethylnaphthalene isomerization AMOCO CORP (US) 1997-01-22 EP disclosed
US-5401892-A Catalytic cyclization AMOCO CORPORATION (US) 1995-03-28 US disclosed
EP-0351074-B1 Preparation of a dimethyltetralin AMOCO CORP (US) 1994-09-07 EP disclosed
EP-0589490-A1 Dimethylnaphthalene isomerization AMOCO CORPORATION (US) 1994-03-30 EP disclosed
US-5284987-A Cyclization of alkenylbenzene feedstock using acid catalyst; removal of the product by distillation concurrent with the addition of feedstock AMOCO CORPORATION (US) 1994-02-08 US disclosed
US-5073670-A Preparation of a dimethyltetralin AMOCO CORPORATION (US) 1991-12-17 US disclosed
US-5030781-A Cyclization of tolyl pentenes or phenyl hexenes using zeolite type y catalyst AMOCO CORPORATION (US) 1991-07-09 US disclosed
US-5012024-A Catalytic dehydrogenation of dimethyltetralins AMOCO CORPORATION (US) 1991-04-30 US disclosed
US-4962260-A ISOMERIZATION IN PRESENCE OF SOLID ZEOLITIC CATALYST AMOCO CORPORATION (US) 1990-10-09 US disclosed
US-4950825-A CATALYTIC CYCLIZATION OF 5-TOLYL-(OR PHENYL-) PENT(HEX)-1 OR 2-ENE USING ZEOLITE CATALYST AMOCO CORPORATION (US) 1990-08-21 US disclosed
EP-0351074-A1 Preparation of a dimethyltetralin AMOCO CORPORATION (US) 1990-01-17 EP disclosed
CN-1038805-A The preparation method of dimethyltetralin AMOCO CORP (US) 1990-01-17 CN disclosed
WO-1989012612-A1 PREPARATION OF A DIMETHYLTETRALIN AMOCO CORPORATION (US) 1989-12-28 WO disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed