Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8176576 | 0.98 | PNMT (0.52) | PNMTDRD4HTR2BTMEM97SIGMAR1 | |
| SCHEMBL6973388 | 0.94 | TMEM97 (0.60) | PNMTDRD4HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7846191 | 0.91 | SIGMAR1 (0.55) | PNMTDRD4HTR2BTMEM97SIGMAR1 | |
| SCHEMBL9314619 | 0.87 | SIGMAR1 (0.55) | DRD4HTR2BTMEM97SIGMAR1ADRA2A | |
| SCHEMBL6966743 | 0.86 | TMEM97 (0.58) | DRD4HTR2BTMEM97SIGMAR1ADRA2A | |
| SCHEMBL3148257 | 0.83 | MEN1 (0.67) | MEN1KMT2ADHFRACHENOS1 | |
| SCHEMBL6962333 | 0.83 | TMEM97 (0.55) | DRD4HTR2BTMEM97SIGMAR1ADRA2A | |
| SCHEMBL31134754 | 0.82 | ACHE (0.66) | PNMTDRD4HTR2BTMEM97SIGMAR1 | |
| SCHEMBL10978742 | 0.82 | ACHE (0.66) | PNMTDRD4HTR2BTMEM97SIGMAR1 | |
| SCHEMBL6972464 | 0.82 | SIGMAR1 (0.52) | PNMTDRD4HTR2BTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162310-A | Bicyclic amidine derivatives used in therapy | ASTRA AB (SE) | 1997-10-15 | — | — | CN | disclosed |
| WO-1997006158-A1 | BICYCLIC AMIDINE DERIVATIVES USEFUL IN THERAPY | ASTRA AKTIEBOLAG (SE) | 1997-02-20 | — | — | WO | disclosed |