Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.35 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464296 | 0.78 | DYRK1A (0.46) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31619545 | 0.75 | ERCC5 (0.53) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6009055 | 0.75 | ERCC5 (0.53) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20276479 | 0.71 | ERCC5 (0.50) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20846095 | 0.69 | KIF11 (0.40) | GAADYRK1ACHEK1EGFR | |
| SCHEMBL8219938 | 0.67 | ERCC5 (0.44) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29178079 | 0.67 | PARP1 (0.38) | GPR84GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9038402 | 0.66 | GPR17 (0.61) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31332450 | 0.66 | GPR17 (0.61) | ERCC5FEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7673751 | 0.64 | GPR17 (0.49) | ERCC5FEN1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |