Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420823 | 0.91 | ALDH1A1 (0.53) | MAPTCA1MAOBNFE2L2CYP3A4 | |
| SCHEMBL14490241 | 0.90 | MAPT (0.41) | MAPTCA1MAOAMAOBPOLB | |
| SCHEMBL13759926 | 0.90 | MAPT (0.41) | MAPTCA1MAOAMAOBPOLB | |
| SCHEMBL482810 | 0.84 | ESR1 (0.59) | MAPTCA1MAOAMAOBPOLB | |
| SCHEMBL13759917 | 0.82 | CYP1B1 (0.45) | MAPTMAOBPOLBRAB9ACYP3A4 | |
| SCHEMBL13759925 | 0.81 | RELA (0.51) | MAPTMAOAMAOBCYP3A4LMNA | |
| SCHEMBL123484 | 0.81 | CA1 (0.48) | MAPTCA1MAOAMAOBPOLB | |
| SCHEMBL23458240 | 0.80 | ALDH1A1 (0.48) | MAPTRAB9ALMNAALDH1A1HPGD | |
| SCHEMBL23458229 | 0.78 | MAOB (0.52) | MAPTMAOBPOLBRAB9ACYP3A4 | |
| SCHEMBL4614234 | 0.78 | MAOB (0.52) | MAPTMAOBPOLBRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705269-B1 | TITANIUM(II) OR ZIRCONIUM(II) COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 1997-01-15 | — | — | EP | claimed |