Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34460318 | 0.87 | HTT (0.70) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL31236033 | 0.87 | HTT (0.70) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL7466908 | 0.85 | KDM4E (0.68) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL6582728 | 0.85 | KDM4E (0.67) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL383122 | 0.85 | GAA (0.51) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL19219043 | 0.84 | KDM4E (0.55) | GAAKDM4ECYP3A4HTTKMT2A | |
| SCHEMBL7457674 | 0.83 | CYP3A4 (0.69) | KDM4ECYP3A4HTTKMT2ARAB9A | |
| SCHEMBL30350316 | 0.83 | CYP3A4 (0.69) | KDM4ECYP3A4HTTKMT2ARAB9A | |
| SCHEMBL20630769 | 0.83 | HTT (0.68) | KDM4ECYP3A4HTTKMT2ARAB9A | |
| SCHEMBL20060067 | 0.82 | KMT2A (0.56) | GAAKDM4ECYP3A4HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |