Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582728 | 0.95 | KDM4E (0.67) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL7378524 | 0.91 | KDM4E (0.73) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL6582726 | 0.87 | LCK (0.60) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL6781993 | 0.85 | KDM4E (0.56) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL31335674 | 0.85 | GAA (0.54) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL19219043 | 0.85 | KDM4E (0.55) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL8900845 | 0.85 | GAA (0.54) | KDM4EKMT2ACYP3A4GAAPOLB | |
| SCHEMBL11317879 | 0.84 | GAA (0.72) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL8900419 | 0.84 | GAA (0.72) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL11568484 | 0.84 | KDM4E (0.76) | KDM4EKMT2ACYP3A4GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767170-B1 | NOVEL 4,6-DIARYLPYRIMIDINE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5786355-A | COMPOUNDS FOR TREATMENT OF CANCER, RHEUMATISM, DIABETIC RETINOPATHY OR PSORIASIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0767170-A1 | NOVEL 4,6-DIARYLPYRIMIDINE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-09 | — | — | EP | disclosed |